PyrimIDine-2,4 (1h, 3h) - cur A'a: 66-22-8

A takaice bayanin:

Sunan sunadarai:Uracil
CAS No.:66-22-8
CASTRECILated CAS:14410-6-7,68-7-7-77-77-77-77-24-24-8-85-85-85-854-6-6 , 5195-19-6,138285-60,153445-42-24-73-710-733-14-7-8-8
Tsarin kwayoyin halitta:C4h4n2o2
Nauyi na kwayoyin:114.089
Lambar HS.:2933.59
Lambar Turai (EC):200-621-9
Lambar NSC:759649,29742,3970
UNII:56h86ZVCT
ID na DSSTOX:Dtxsid40021424
Lambar Nikkaji:J4.842i
Wikipedia:Uracil
Wikidata:Q182990
Lambar NCI Thesaurus:C917
Idetholomics Workbench ID:37192
Chembl id:Chembl566
Fayil na Mol:66-22-8.mol

Aika imel zuwa gare mu

Cikakken Bayani

Tags samfurin

Kwatanci: Uracil

Kayan masana'antu na pyraridine-2,4 (1h, 3h) -Dione

Bayyanar / launi: farin foda
● Trapher matsa lamba: 2.27e-08mmhg a 25 ° C
Point ● Melting Points:> 300 ° C (lit.)
Index index: 1.501
● Bhazadi mai tafasa: 440.5 ° C a 760 mmhg
● Poka: 9.45 (a 25 ℃)
● FASTTON: 220 biyuoc
● PSA:65.72000
● Ganantawa: 1.322 g / cm3
● Laja: -0.93680

● Storest Temp.:+ ::+
● Sulilility.:Aqueous acid (dan kadan), DMSO (dan kadan, mai zafi, Sonanol (dan kadan,
● Cikin ruwa mai amfani da ruwa
● Xlogp3: -1.1
● Hydrogen Bond Donor Kidaya: 2
● Hydrogen Bond Reador: 2
● Haɗin Bond: 0
● daidai taro: 112.027277375
● CIGABA DA ATOM Kidaya: 8
● Hadadewa: 161

Bayanin Safya

● Picogram (s):XI
Lambobin Hadiki: Xi
Bayanin lafiya: 22-24 / 25

M

A Daraktsan Kwarewar:Ma'aikatan nazarin halittu -> Nukulan nucleic da abubuwan da suka dace
Canonical murmushi:C1 = CNC (O) NC1 = O
Kwanan nan asibiti:Nazarin 0.1% Uracill Tarihi (UTC) don rigakafin cututtukan ƙafa
Tarihin EU na yanzu na EU:Ondereek Naar de Farmacoketiek van Uracil Na Orale Teediening Bij Patti? Neten haduwa da Colorectaal Carcinoom.
Gwajin Asibiti na kwanan nan: Gwajin II na magudi na maganin iracick na maganin shafawa na Capecitabine wanda ya jawo hankalin mutum-ƙafa (HFS):.
Amfani:Don Binciken Biochemical, magunguna suna kira; Ana amfani da shi azaman tsaka-tsaki na magunguna, wanda aka yi amfani dashi a cikin kwayar halitta nitrogenous kafa akan RNA Nucleclesions. antineoplact cikin binciken biochemical. Uracil (Lamivudine Ep Honey F) shine tushen nitrogenous akan RNA Nucleclesides.
Bayanin:Uracil wani tushe ne na pyriridine kuma wani babban sashi na RNA inda ya ɗaure zuwa adenine ta hanyar hydrogen shaidu. An canza shi a cikin nucleoside rideine ta hanyar daɗaɗɗen ribiya, to to nucleotide ridepphate ta hanyar ƙungiyar phosphate.

Cikakken gabatarwar

Uracil wani fili ne na kwayoyin halitta wanda yake na dangin pyraridine. Molejin heeterocycule ne wanda ya kunshi zobe pyrimidine tare da zoben nitrogen biyu na nitrogen. Uracil yana da tsarin sunadarai C4h4n2o2 da nauyin kwayar halittar 112.09 g / mol.
Uracil yana daya daga cikin abubuwan nucleobases hudu da aka samu a cikin kayan halittar RNA (rabinukin hakarufin). Yana taka muhimmiyar rawa a cikin furotin mai gina jiki da kuma magana ta gari. A cikin RNA, Urarri nau'i-nau'i tare da adenine ta hanyar haɗin hydrogen, samar da shaidu na hydrogen biyu, kuma wannan tushe ya taimaka wajen letato bayanai.
Hakanan za'a iya samun hanyar Uracil a wasu mahimman kwayoyin halitta. Misali, bangare ne mai mahimmanci na kwayoyin da ake kira ATP (Adenosine Triphosphate). Uracil abubuwan kare, kamar 5-fluoroacillill, an yi amfani da su a matsayin wakilai na maganin anticancer saboda ikon yin tsoma baki da rarraba sel.
Baya ga mahimmancin ilimin halittar ta, Uracil yana da daban-daban aikace-aikace na masana'antu da masana'antu. Ana amfani dashi azaman kayan farawa don synthumenis na magunguna, agrochemicals, da dyes. Hakanan ana amfani da abubuwan da Uracil a cikin samar da herbicides da fungicides. Bugu da ƙari, za a iya amfani da Urasick a matsayin alama a cikin nazarin ilmin sunadarai kuma a matsayin kayan aiki a Bincike Binciken Bincike na kwayoyin halitta.
Uracil shine farin lu'uluji wanda yake da hankali sosai cikin ruwa. Ana iya tsayayye a ƙarƙashin yanayin al'ada amma zai iya ƙasashen sunadarai, kamar iskar shaye-shaye da musanya su, ƙarƙashin yanayi takamaiman yanayi. Gibiyar tana da ma'anar narkewa na 335-338°C da tafasa na 351-357°C.
Gabaɗaya, Uracil wani abu ne mai mahimmanci a cikin tsarin halittar RNA kuma yana da mahimman aikace-aikace a duka halittu biyu da masana'antu masu guba.

Roƙo

Uracill yana da aikace-aikace da yawa a fannoni daban daban, gami da:
Masana'antar masana'antu:Uracil da abubuwan da aka yi amfani da su don haɓaka kwayoyi don dalilai daban-daban. Misali, 5-Flooroacil miyagun ƙwayoyi ne da aka saba amfani dasu ne don magance wasu nau'ikan cutar kansa. Uracill-tushen kwayoyi masu maganin rigakafi, kamar su na Idoxuridine da tsibiri, ana amfani dasu don magance cututtukan ido na hoto.
Noma:Ana amfani da abubuwan haɗin Uracil a cikin samar da herbicides da fungicides. Waɗannan mahadi suna taimakawa sarrafa haɓakar ciyawa da kuma kare albarkatu daga cututtukan fungal.
Analystistry Chemistry:Ana amfani da Uracil a matsayin alamar Chromatographic ko Standard a cikin hanyoyin sunadarai na nazari. Ana iya amfani da shi azaman fili don tantance lokacin riƙewa da kuma amfani da sauran mahadi a cikin samfurin.
Kwayoyin halitta na kwayoyin halitta:Uracil ana amfani dashi a cikin dabaru iri iri-iri, kamar su polymores sarkar dauki (PCR), DNA SEQENTINCE, da kuma shafin-da-direcle mutageneis. Yana aiki a matsayin samfuri don DNA SYTHESIS ko azaman haɗin gwiwar musamman maye gurbi a cikin jerin DNA.
Masana'antar Abinci:Lokaci-lokaci ana amfani dashi lokaci-lokaci azaman dandano mai tasowa a cikin masana'antar abinci, musamman a cikin samar da abinci da abubuwan sha.
Kayan kwalliya:Ana amfani da abubuwan haɗin Uracil a cikin samfuran kwaskwarima don moisturizing da kadarorin fata na fata. Zasu iya taimakawa inganta hydration na fata da karewa daga masu maye gurbin muhalli.
Bincike da Ci gaba:Hakanan ana amfani da UracIl a cikin bincike na Biochemical da magunguna a matsayin sake farfadowa ko tsaka-tsaki don haɓaka sauran mahadi tare da aikin halittu ko don nazarin metabilic acid.
Manyan bayanan Uracil na nuna mahimmancin filayen kamar magani, noma, sunadarai, da ilimin kimiya. Masu bincike suna ci gaba da bincika sabbin hanyoyin da za su yi lalata da kadarorin su don ƙarin ci gaba a waɗannan yankuna.