Kaya
N, N'-Diisopropylcarbodide; CAS A'a.: 693-13-0 zuba
Kwatanci: 1,3-Diisopropylcarbarkiide
Sursere Dealm n, N'-Diisopropylcarbodide
Bayyanar / launi: mai launi ga kodadde mai launin shuɗi
● Traphate matsa lamba: 34.9hpa a 55.46 ℃
Fasali na Musamman: 210-212 ° C (de)
● Magana mai ban sha'awa: N20 / D 1.433 (LIT.)
● Poust aya: 146.5 ° C a 760 mmhg
● Flashta: 33.9 ° C
● PSA:24.72000
● Tattaunawa: 0.83 g / cm3
● Laja: 1.97710
● Stage Templ.: 7
● Mai hankali.:
● Sulilility.:Soluble a cikin chloroform, methylene chloride, acetonitrile, dioxanerane
● Xlogp3: 2.6
● Hydrogen Bond Donor Kidaya: 0
● Hydrogen Bond Reador: 2
Tashar Bond Counts: 2
● daidai taro: 126.115698455
● Kididdige da atom count: 9
Hadadun gaba: 101
Bayanin Safya
● Pictogram (s): t +,
T,
F
Lambobin Hazard: T +, T, F, XN
● Bayani: 10-26 / 38 / 38/01-42-44-37 / 38
Bayanin Tsaro: 26-36 / 39 / 395-38-28A-16-22
M
A Daraktsan Kwarewar:Tsarin Nitrogen -> Sauran mahadi Nitrogen
Canonical murmushi:Cc (c) n = c = c = c
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Bayanin kwatancen (DIC) ruwa ne bayyananne wanda za'a iya rarraba shi ta hanyar girma. Yana sannu a hankali ya yi da danshi daga iska, don haka don dogon ajiya ajiya ya kamata a flushed da busassun iska ko iska mai rauni. Ana amfani dashi a cikin sunadarai na peptide azaman maimaitawa. Yana da matukar guba da kuma haduwa da cututtukan dermatitis a cikin ma'aikatan dakin gwaje-gwaje.
Amfani:Wannan samfurin ana amfani da shi a cikin amikacin, glutatHoni dehydrants, da kuma a cikin kira na acid anhydride, isochyanate; Lokacin da ake amfani dashi azaman mai bushewar haske, yana amsawa ga oticlohylurea ta hanyar ɗan gajeren lokaci a ƙarƙashin yanayin zafin jiki na al'ada. Hakanan za'a iya amfani da wannan samfurin a cikin kira na ptifide da nucleic acid. Abu ne mai sauki ka yi amfani da wannan samfurin don amsawa tare da mahimmin ɗakin carbox kyauta da amino-rukuni cikin peptide. Ana amfani da wannan samfurin sosai a cikin likita, lafiya, kayan shafa da samfuran tazarin halittu, da sauran filayen roba. N, N'-Diisopropylcaropylcaropylcarbodide azaman sake farfadowa a roba na roba. Yana aiki a matsayin matsakaici na sunadarai kuma a matsayin maimaitawa don Sarin (makamin keyru na sinadarai). Hakanan ana amfani dashi a cikin tsarin peptide da nucleic acid. Bugu da ari, ana amfani dashi azaman agineopra na motsa jiki da hannu wajen lura da maganin Meleloma da saba. Baya ga wannan, ana amfani dashi a cikin tsarin acid anhydride, Aldehyde, keten da isocyanate.
Cikakken gabatarwar
N, N'-Diisopropylcarbodide, da aka saba yankewa kamar DIC, sanda ne mai guba tare da dabarun sinadarai c7h14N2. Wani ruwa ne mai launi mara launi wanda yake narkewa a cikin abubuwanda ke cikin halitta kamar kursiyin da suka yi. Dic an yi amfani da shi sosai azaman kayan aikin kwayar halitta kuma yana taka muhimmiyar rawa a cikin halayen sunadarai daban-daban.
DIC da farko ake amfani dashi azaman wakili mai hada-hade a cikin Peptide Synthesis, wanda shine aiwatar da haɗuwa da amino acid tare don samar da peptides ko sunadarai. Yana aiki a matsayin mai ban sha'awa na mai da hankali, yana sauƙaƙe hada amino acid din ta hanyar kunna ƙungiyõshin tsaka-tsaki da ake kira mai aiki. Wannan yanayin tsaka-tsaki tare da aminoungiyoyi kafin a shirya kayan da kuma kawar da su samar da peptide.
DIC shima ana amfani da shi a wasu halayen bayan peptide kira na peptide, irin su estersifications, amdadin, da uracehane synthesis. Yana aiki azaman wakili mai narkewa a cikin waɗannan halayen, yana sauƙaƙe cire kwayoyin ruwa, ta hakan ne ta gaba da halayen da ake so a gaba.
Sakamakon amsawarsa da ƙanshin ƙarfi, yakamata a kula da dic tare da taka tsantsan. A yawanci ana amfani dashi a cikin hood-ventilated fue hood da safofin hannu na kariya yakamata a sawa don hana fata lamba. Bugu da ƙari, kamar yadda tare da kowane sinadarai, yana da mahimmanci bi tsarin aminci daidai kuma ku nemi takardar tsarin amincin kayan aiki (MSDs) don cikakken bayani.
A taƙaice, N, N, N, N'-Diiscroodipylcarbodide ne mai son sake yin amfani da shi a cikin halayen kwayoyin halitta, gami da aikin peptide, hade da etrethane synthesis. Matsayinta a matsayin wakili mai hada kai da wakili na bushe-bushe yana sa kayan aiki mai mahimmanci ne a fagen sunadarai na kwayoyin.
Roƙo
N, N'-Diisopropylcarbodifimiide (DIC) yana da aikace-aikace da yawa masu mahimmanci a cikin kwayoyin halitta da bincike na magunguna. Anan akwai wasu takamaiman amfani na DIC:
Peptide Synthesis:Dic an saba amfani dashi azaman wakili mai haɗa a cikin m-mayi peptide kira don samar da peptide pep acid. Yana kunna ƙungiyoyin carboxyl na kariya gaino acid, yana ba su damar yin amsa tare da ƙungiyoyin Amino, wanda ya haifar da samuwar peptide.
Rashin daidaituwa da halayyar hade da juna:DIC yana aiki azaman wakili mai narkewa don inganta sandar carball din carboxylic acid tare da amsanci ko halayen hade da juna, bi da bi. Yana sauƙaƙe samuwar balsesies da matattu ta cire ruwa daga cakuda dauki.
Urethane kira:Za'a iya amfani da DIC azaman wakili mai haɗawa a cikin kira na mahaɗan urethane. Yana ba da damar amsawa tsakanin isocyanates da giya don samar da Urethanes.
Carbodide-da aka yi masa alama da aka daidaita halayensu:An yi amfani da DIC sau da yawa azaman haɗuwa mai yawa a cikin nau'ikan halayen kwayoyin halitta, kamar synthesis na amsiges, peptiges, da sauran abubuwan da ke aiki na biologically. Yana inganta haɗarin carboxylic acid, crlorides na acid, ko acyl hoides tare da Amines, hydroxylamines, da sauran nucleophiles.
Canjin ciki:DIC za a iya amfani da su a cikin halayen marasa amfani, kamar su na oilins na oilins da hadawan abu da iskar-shaka zuwa sulfoxides ko sulfones.
Yana da mahimmanci a lura cewa DIC shine Air- da danshi-m, don haka ya kamata a kula da wani yanki mai kyau ko a ƙarƙashin yanayin Inest. Bugu da ƙari, matakan tsaro, kamar safofin hannu da gwangwani, ya kamata a ɗauka yayin aiki tare da dabi'ar da ta haɗari.
