Kaya
Di-teert-butyl Dicarbonate; CAS A'a.: 24424-99-5
Kwatanci: BIS (Tert-ButoxycarlonyL) oxide; BOC (2) O CPD; BOC2O CPD; DI-Tert-bututun fasik
Kayan sunadarai na Di-Tert-butyl Dicarbonate
Bayyanar / launi: fari don kashe-farin microcrystalline foda
● Trapher matsa lamba: 0.7mmhg a 25 ° C
Point ● Melting Points: 22-24 ° C
Indeve Index: 1.4090
● aya mai tafasa: 235.8 ° C a 760 mmhg
● FASHT FASBT: 103.7 ° C
● PSA:61.83000
Bensity: 1.054 g / cm3
● Laja: 2.87320
● Stage Templ.: 7
● Mai hankali.:
● Wuri na SOLUQULI.: A cikin Decalin, Toluene, Carbon Tetrachlloride, Tetrohyrofugan, Dioxane, barasa, acetone, acetone, acetone, acetone, acetone, acetelflorm
● Xlogp3: 2.7
● Hydrogen Bond Donor Kidaya: 0
● Hydrogen Bond Karatun: 5
● LORAaccable Bond: 6
● daidai taro: 218.11542367
● Kididdige Terom Count: 15
Komadan gaba: 218
Bayanin Safya
● Picogram (s):
T, t +,
F, F +,
XI
Lambobin Hazard: T +, T, F, Xi, F +
● Bayani: 11-19-26 / 38/03-10-10-40
Bayanin Tsaro: 16-26-28 / 37-7 / 9/37 / 39-24 / 39-24-30 / 39 / 39-33 / 39-33
M
A Daraktsan Kwarewar:Wasu azuzuwan -> esters, wasu
Canonical murmushi:Cc (c) (c) oc (= o) oc (= o) oc (c) oc (c) (c) c
Amfani:Di-Tert-Butyl Dicarbonate (BOC2o) sake amfani da shi sosai don gabatar da kare kungiyoyin peptide. Yana taka muhimmiyar rawa a cikin shirye-shiryen 6-Acetyl-1,2,4,4-Tetrahydroroine ta hanyar maido da 2-piperidone. Yana aiki a matsayin rukuni na kare rukuni da aka yi amfani da shi a cikin daskararren lokaci ptiptide kira.
Cikakken gabatarwar
Di-teert-butyl dicarbonateshine sake yin amfani da shi a cikin tsarin kirkirar halitta. Hakanan ana kiranta da T-Boc anhydride ko bec anddride. Ana amfani dashi don kare ƙungiyoyi na yau da kullun yayin halayen sunadarai. Di-Tert-butyl Dicarbonate yana da hayan tare da Amine na ɗan lokaci don ƙungiyar Amine. Da zarar amsar da ake so ta cika, ana iya cire rukunin carbamate ta hanyar magani da acid, mai samar da ainihin ayyukan amine. Wannan dabara ce mai amfani don canza wasu kungiyoyin aiki a cikin kwayoyin halitta.
Roƙo
Baya ga kare kungiyoyi, di-tetrt-butyl Dicarbonate yana da daban-daban aikace-aikace a cikin kwayoyin halitta:
Kariyar kungiyoyin Hydroxyl:Di-Tert-butyl Dicarbonate na iya amsawa da giya don samar da carbonates, kare hydroxyl rukuni. Daga nan sai a cire rukunin Carbonate sannan a cire ta amfani da yanayin da suka dace, ba da izinin canji na sauran ƙungiyoyin ayyukan.
Tunani na CarbonyDI-Tert-butyl Dicarbonate za a iya amfani da shi azaman tushen Carbon Monoxide a cikin Carbony halayen. Yana da alaƙa da abubuwan da nucleophiles kamar Amarya, barasa, da thiols don samar da samfuran carbony.
Shiri na acid chlordids:Reating Di-Tert-butyl Dicarbonate tare da Thionyl chloride ko oxalyl chloride yana samar da ciyawar acid na acid. Aci chlorides suna da fifiko mai mahimmanci wanda aka yi amfani da su a cikin nau'ikan abubuwan haɗin roba.
M-m-lokaci peptide kirnthesis:DI-Tert-butyl Dicarbonate ana amfani da amfani da shi a cikin kariya da matakai na matattara a cikin m-lokaci peptide kira. Ana amfani dashi don kare amino acid a lokacin fadada sarkar kuma don cire ƙungiyoyi masu zuwa don fitar da ƙungiyoyin amino don halayen masu zuwa tare da dunkulewa.
Kasancewar ayyukan Polymerization:Di-Tert-butyl Dicarbonate na iya yin aiki azaman wakilin canja wuri a cikin yarjejeniyar polymerization halayen. Zai iya amsawa tare da girma polymer sarƙoƙi, dakatar da haɓakar su ko samar da sabon kayan aiki.
Waɗannan 'yan misalai ne kawai na aikace-aikacen Di-teert-butyl Dicarbonate a cikin kwayoyin halitta. Ta hanyar amfani da sauƙin amfani da shi ya sanya shi mai mahimmanci mai mahimmanci a cikin canjin sunadarai daban-daban.
