Kayayyaki
2,4-Diamino-6-hydroxypyrimidine
Hydroxypyrimidine Chemical Properties
| Wurin narkewa | 285-286 ° C (dare) (lit.) |
| Wurin tafasa | 234.22°C (m kiyasin) |
| yawa | 1.3659 |
| refractive index | 1.7990 (ƙididdiga) |
| yanayin ajiya. | Ajiye a cikin duhu wuri,Inert yanayi, daki zazzabi |
| narkewa | DMSO (Dan kadan), methanol (dan kadan) |
| pka | 10.61± 0.50 (An annabta) |
| tsari | Fine Crystalline Foda |
| launi | Fari zuwa kirim |
| M | Hasken Hannu |
| Merck | 14,2981 |
| BRN | Farashin 125006 |
| InChiKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
| Bayanan Bayani na CAS DataBase | 56-06-4(CAS DataBase Reference) |
| Bayanin Chemistry NIST | 4 (1H) -pyrimidinone, 2,6-diamino-(56-06-4) |
| Tsarin Rijistar Abun EPA | 2,6-Diamino-4(1H) -pyrimidinone (56-06-4) |
Bayanin Samfuran Hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine wani sinadari ne mai hade da tsarin kwayoyin C4H6N4O.Wani fili ne na kwayoyin halitta na dangin pyrimidine.Filin yana da tsarin zobe na pyrimidine, ƙungiyoyin amino guda biyu (NH2) an haɗa su a matsayi na 2 da 4, kuma an haɗa ƙungiyar hydroxyl (OH) a matsayi na 6.Ana iya bayyana tsarin sinadarai kamar: Ammoniya ||H--C--C--C--N--C--C--NH2 ||oh 2,4-Diamino-6-hydroxypyrimidine yana da aikace-aikace daban-daban a cikin masana'antar harhada magunguna.Yana da mahimmancin tsaka-tsaki a cikin haɗin magunguna da yawa, ciki har da magungunan ƙwayoyin cuta da ƙwayoyin cuta.Hakanan ana amfani dashi don samar da analogues na nucleotide da yawa da aka yi amfani da su a cikin binciken magunguna.
Baya ga aikace-aikacen magunguna, 2,4-diamino-6-hydroxypyrimidine kuma ana amfani dashi azaman sinadari a cikin agrochemicals.Yana da wani muhimmin sashi a cikin kira na masu kula da ci gaban shuka da fungicides.Yana da matukar muhimmanci a bi ka'idar aminci mai kyau lokacin amfani da 2,4-diamino-6-hydroxypyrimidine.Tunda an rarraba shi azaman sinadari mai ban haushi, yakamata a kula dashi tare da kulawa kuma yakamata a sanya isassun kayan kariya na mutum don gujewa hulɗa kai tsaye.
A taƙaice, 2,4-diamino-6-hydroxypyrimidine wani nau'in halitta ne tare da aikace-aikace a cikin magunguna da filayen noma.Tsarin sinadaransa ya sa ya zama mai amfani a matsayin tsaka-tsaki a cikin haɗin magunguna da masu kula da ci gaban shuka.
Bayanin Tsaro
| Lambobin haɗari | Xi |
| Bayanin Hatsari | 36/37/38 |
| Bayanan Tsaro | 22-24/25-36-26 |
| WGK Jamus | 3 |
| Bayanin Hazard | Haushi |
| Farashin TSCA | Ee |
| HS Code | 29335995 |
Amfani da Hydroxypyrimidine da Ƙarfafawa
| Bayani | 2,4-Diamino-6-hydroxypyrimidine (DAHP) wani zaɓi ne, takamaiman mai hanawa na GTP cyclohydrolase I, matakin ƙayyadaddun ƙayyadaddun ƙayyadaddun matakan de novo pterin kira.A cikin sel HUVEC, IC50don hana BH4biosynthesis shine kusan 0.3 mM.Ana iya amfani da DAHP don toshe NO samarwa a cikin nau'ikan tantanin halitta yadda ya kamata. |
| Abubuwan Sinadarai | Farin Tauri |
| Amfani | 2,4-Diamino-6-hydroxypyrimidine (DAHP) wani zaɓi ne, takamaiman mai hanawa na GTP cyclohydrolase I, matakin ƙayyadaddun ƙayyadaddun ƙayyadaddun matakan de novo pterin kira.A cikin ƙwayoyin HUVEC, IC50 don hana BH4 biosynthesis shine kusan 0.3 mM.Ana iya amfani da DAHP don toshe NO samarwa a cikin nau'ikan tantanin halitta da yawa.[Cayman Chemical] |
| Amfani | Yana tsaye ne a farkon kascade na enzyme-catalyzed wanda ya fara da wannan carbohydrate-carbon carbohydrate kuma ya ƙare da amino acid phenylalanine, tyrosine, da tryptophan. |
| Amfani | 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) wani fili ne da ke da amfani a cikin haɗakar halitta. |
| Hanyoyin Tsarkakewa | Yana recrystallises daga H2O.[Beilstein 25 III/IV 3642.] |
