Kayayyaki
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Synonyms: 4 (1H) -Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4 -dihydropyrimidin-4-daya; 2,6-Diamino-4 (1H) -pyrimidinone;2,6-Diamino-4 (3H) -pyrimidinone; 2,6-Diamino-4-hydroxypyrimidine;2,6-Diamino-4 -pyrimidinol; 2,6-Diaminopyrimidin-4-daya;2,6-Diaminopyrimidine-4 (3H) -daya; 6-Aminoisocytosine; 6-Hydroxy-2,4-pyrimidinediamine; NSC 44914; NSC 680818; NSC9302;
Abubuwan Sinadarai na 2,4-Diamino-6-hydroxypyrimidine
● Siffar/Launi: farin m
● Ruwan tururi: 0.00232mmHg a 25 ° C
● Matsayin narkewa: 285-286 ° C ( Dec.) (lit.)
● Fihirisar Magana: 1.7990 (ƙididdigar)
● Matsayin tafasa:288.5 °C a 760 mmHg
● PKA: 10.61 ± 0.50 (An annabta)
● Fitilar Fila: 128.3 °C
PSA: 98.05000
● Girma: 1.84 g / cm3
● LogP: 0.50900
● Yanayin Ajiye: Yanke a +4°C
● Hankali.: Hasken Hankali
● Solubility.: DMSO (dan kadan), methanol (dan kadan)
Tsafta / inganci
99% * bayanai daga danyen kaya
2,4-Diamino-6-hydroxypyrimidine * bayanai daga masu samar da reagent
Bayanin Tsaro
● Hoton(s):
Xi
● Lambobin haɗari: Xi
● Bayani: 36/37/38
● Bayanan Tsaro: 22-24 / 25-36-26
Fayilolin MSDS
Mai amfani
● Bayani: 2,4-Diamino-6-hydroxypyrimidine (DAHP) wani zaɓi ne, mai hanawa na musamman na GTP cyclohydrolase I, matakin ƙayyadaddun ƙayyadaddun matakan de novo pterin kira.A cikin ƙwayoyin HUVEC, IC50 don hana BH4 biosynthesis shine kusan 0.3 mM.Ana iya amfani da DAHP don toshe NO samarwa a cikin nau'ikan tantanin halitta yadda ya kamata.
● Yana amfani da: 2,4-Diamino-6-hydroxypyrimidine (DAHP) zaɓi ne, takamaiman mai hanawa na GTP cyclohydrolase I, matakin ƙayyadaddun ƙayyadaddun ƙimar de novo pterin kira.A cikin ƙwayoyin HUVEC, IC50 don hana BH4 biosynthesis shine kusan 0.3 mM.Ana iya amfani da DAHP don toshe NO samarwa a cikin nau'ikan sel da yawa. 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) wani fili ne da ke da amfani a cikin haɗakar halitta.
2,4-Diamino-6-hydroxypyrimidine wani sinadari ne mai hade da tsarin kwayoyin C4H6N4O.Ana amfani da shi a matsayin tsaka-tsakin tsaka-tsaki a cikin haɗuwa da nau'o'in mahadi daban-daban, ciki har da magungunan magunguna da dyes. Filin yana da tsarin zobe na pyrimidine wanda ya ƙunshi ƙungiyoyi biyu na amino (NH2) da kuma ƙungiyar hydroxyl guda ɗaya (OH) da aka haɗe zuwa nau'in atom na carbon daban-daban.Wannan tsarin ya sa ya zama tubalin ginin gine-gine don haɗakar da ƙarin hadaddun kwayoyin halitta.2,4-Diamino-6-hydroxypyrimidine za a iya samu ta hanyoyi daban-daban na roba, ciki har da amsawar cyanamide tare da urea.Yana da aikace-aikace da yawa a cikin masana'antar harhada magunguna, musamman a cikin haɗin magungunan anticancer da maganin rigakafi. Gabaɗaya, 2,4-Diamino-6-hydroxypyrimidine wani muhimmin fili ne wanda ke samun amfani a cikin nau'ikan sinadarai da aikace-aikacen magunguna.
